The theme of the third annual Spring workshop of the HUPO-PSI was proteomics and beyond and its underlying goal was to reach beyond the boundaries of the proteomics community to interact with groups working on the similar issues of developing interchange standards and minimal reporting requirements. Significant developments in many of the HUPO-PSI XML interchange formats, minimal reporting requirements and accompanying controlled vocabularies were reported, with many of these now feeding into the broader efforts of the Functional Genomics Experiment data (...) model and Functional Genomics Ontology ontologies. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

To create fair and accountable AI and robotics, we need precise regulation and better methods to certify, explain, and audit inscrutable systems.

Recent calls to address racism in bioethics reflect a sense of urgency to mitigate the lethal effects of a lack of action. While the field was catalyzed largely in response to pivotal events deeply rooted in racism and other structures of oppression embedded in research and health care, it has failed to center racial justice in its scholarship, pedagogy, advocacy, and practice, and neglected to integrate anti-racism as a central consideration. Academic bioethics programs play a key role in determining the (...) field’s norms and practices, including methodologies, funding priorities, and professional networks that bear on equity, inclusion, and epistemic justice. This article describes recommendations from the Racial Equity, Diversity, and Inclusion (REDI) Task Force commissioned by the Association of Bioethics Program Directors to prioritize and strengthen anti-racist practices in bioethics programmatic endeavors and to evaluate and develop specific goals to advance REDI. (shrink)

Taking a pragmatist stance toward the practices and products of science shapes our answers to central philosophical questions. In argue that from within a perspective consisting of goals, actions and questions, what we say there is and what we say it does, is justified by the ongoing interactions among representative models, causal experience and experiment, and conceptual frameworks in reaching a fallible convergence to what is real. I offer a non-dichotomous alternative. I propose an alternative to fundamentalist approaches, arguing that (...) what we are justified in claiming as real phenomena are the affordances constructed from the integration of top-down and bottom-up strategies. (shrink)

Feminist standpoint theory remains highly controversial: it is widely advocated, used to guide research and justify its results, and yet is also vigorously denounced. This essay argues that three such sites of controversy reveal the value of engaging with standpoint theory as a way of reflecting on and debating some of the most anxiety-producing issues in contemporary Western intellectual and political life. Engaging with standpoint theory enables a socially relevant philosophy of science.

Using classical American pragmatism, the authors provide a philosophical framework for rethinking the nature of the corporation--how it is embedded in its natural, technological, cultural, and international environments, emphasizing throughout its pervasive relational and moral dimensions. They explore the relationship of this framework to other contemporary business ethics perspectives, as well as its implications for moral leadership in business and business education.

The scope and method of logic as we know it today eminently reflect the ground-breaking developments of set theory and the logical foundations of mathematics at the turn of the 20th century. Unfortunately, little effort has been made to understand the idiosyncrasies of the philosophical context that led to these tremendous innovations in the 19thcentury beyond what is found in the works of mathematicians such as Frege, Hilbert, and Russell. This constitutes a monumental gap in our understanding of the central (...) influences that shaped 19th-century thought, from Kant to Russell, and that helped to create the conditions in which analytic philosophy could emerge. -/- The aim of Logic from Kant to Russell is to document the development of logic in the works of 19th-century philosophers. It contains thirteen original essays written by authors from a broad range of backgrounds—intellectual historians, historians of idealism, philosophers of science, and historians of logic and analytic philosophy. These essays question the standard narratives of analytic philosophy’s past and address concerns that are relevant to the contemporary philosophical study of language, mind, and cognition. The book covers a broad range of influential thinkers in 19th-century philosophy and analytic philosophy, including Kant, Bolzano, Hegel, Herbart, Lotze, the British Algebraists and Idealists, Moore, Russell, the Neo-Kantians, and Frege. (shrink)

This work runs counter to the traditional interpretations of Peirce's philosophy by eliciting an inherent strand of pragmatic pluralism that is embedded in the very core of his thought and that weaves his various doctrines into a systematic ...

ABSTRACT Genevieve Lloyd argues that when we follow Spinoza in understanding reason as a part of nature, we gain new insights into the human condition. Specifically, we gain a new political insight: we should respond to cultural difference with a pluralist ethos. This is because there is no pure universal reason; human minds find their reason shaped differently by their various embodied social contexts. Furthermore, we can use the resources of the imagination to bring this ethos about. In my response, (...) I offer a friendly challenge to Lloyd’s characterisation of the lessons of Spinoza’s philosophy. I argue that Lloyd’s Spinoza remains excessively unpolitical, even in the moment that he is brought to bear on contemporary politics. An unpluralistic attitude may well be rationally inferior, but is it really explained by insufficient or inappropriate imagination? To the contrary, a properly Spinozist account of reason must include an account of the concrete determinants of reason’s imperfect realisation in the world. In Spinoza’s own oeuvre, this is carried out through an ever-increasing—and ever more sociological—interest in the political structures within which individual reason flourishes or withers. (shrink)

James articulates and defends a Spinozist view of the interplay between poetry and philosophy: philosophy has an ineliminably poetic content, and poetry is an aid and support to philosophy. In this piece, I juxtapose James’s Spinozist schema with another schema available within Spinoza’s historical milieu. In Ibn Tufayl’s view, rather than poetry being an aid to philosophy, poetry opens to a world of experience that even the best philosophy cannot grasp. For flat-footed philosophers who think that philosophy can in principle (...) have the last word on everything, poetics might give an approximate indication of a kind of experience that lies beyond it. (shrink)

This paper presents a novel analysis of Sluicing, an ellipsis construction first described by Ross (1969) and illustrated by the bracketed portion ofI want to do something, but I'm just not sure [what _]. Starting from the assumption that a sluice consists of a displaced Wh-constituent and an empty IP, we show how simple and general LF operations fill out the empty IP and thereby provide it with an interpretable Logical Form. The LF operations we appeal to rely on the (...) influential theory of indefinites developed by Irene Heim and Hans Kamp, and are in harmony with certain aspects of Chomsky's Minimalist Program for linguistic theory. The analysis accounts directly for the familiar properties of Sluicing, as well as some facts which have not previously been observed. (shrink)

ABSTRACTCommentators have generally seen the compassionate person as a second-rate character vis-à-vis the ascetic ‘saint’ who denies the will-to-life and resigns from willing altogether in Schopen...

According to a recent interpretive orthodoxy, Spinoza is a profoundly democratic theorist of state authority. I reject this orthodoxy. To be sure, for Spinoza, a political order succeeds in proportion as it harnesses the power of the people within it. However, Spinoza shows that political inclusion is only one possible strategy to this end; equally if not more useful is political exclusion, so long as it maintains what I call the depoliticised acquiescence of those excluded.

Meta-governance is Earth system governance for dealing with the global commons. This article develops a whole network approach to meta-governance to explore the potential for collective action for sustainable development by a loosely coupled network of networks. Networked corporate social responsibility governance has emerged around corporate sustainability and responsibility in the first years of the 21st century. Growing agreements and interactions among CSR initiatives suggest the development, structure, and governance of networked CSR governance as a network that can analytically be (...) viewed as a whole and as a platform for learning about systemic change. Using the evolution of CSR initiatives from about 1990 to 2014, the authors differentiate four developmental stages: independent and fragmented multistakeholder networks as CSR governance, collaborative CSR governance, networked CSR governance, and integrated networked CSR governance. The authors then present a framework to analyze networked CSR governance as a whole network experimenting with meta-governance. (shrink)

This paper aims to bring together the appeal to the ordinary in the ethics of care and the ‘destruction’ or philosophical subversion which Wittgenstein references in his Philosophical Investigations: Where does our investigation get its importance from, since it seems to destroy everything interesting, all that is great and important? What we are destroying is nothing but houses of cards. The paper pursues a connection between the ethics of care and ordinary language philosophy as represented by Wittgenstein, Austin and Cavell, (...) in particular in a feminist perspective. The central point of Carol Gilligan’s In a Different Voice may not be the idea of a ‘feminine morality’ but a claim for an alternative form of morality. Gilligan’s essay seeks to capture a different, hitherto neglected yet universally present alternative ethical perspective, one easy to ignore because it relates to women and women’s activities. The ethics of care recalls a plea for ‘realism’; in the sense given to it in Cora Diamond’s The Realistic Spirit to mean the necessity of seeing (or attending to) what lies close at hand. Reflection on care brings ethics back to everyday practice much as Wittgenstein sought to bring language back from the metaphysical level to its everyday use. (shrink)

Pseudo-profound bullshit refers to statements designed to impress but lacking in meaning. Due to the discrepancy between philosophical and psychological perspectives on bullshit, there is limited empirical evidence supporting its defining characteristics. This study aimed to test whether these characteristics are indeed distinctive to bullshit and influence the tendency to perceive it as profound. Additionally, recognising that context shapes bullshit receptivity, the second aim was to investigate whether bullshit features influence changes in receptivity when the reliability of an added source (...) varies. Results indicate that participants can identify both meaninglessness and intention to impress in different types of statements. Furthermore, the intention to impress elicits greater changes in profundity evaluations than the meaningfulness of the statement. Finally, both reliable and unreliable sources affect profundity ratings, with these effects observed across all statement categories. (shrink)

A philosophical exploration of the meaning and significance of friendship.This book explains the persistence of friendship today in the light of the history of philosophical approaches to the subject. It considers ideals of intimacy and fusion in the context of claims that such ideals are unrealistic and even dangerous. Cicero's scepticism about friendship in the public realm is compared with the Aristotelian view of friendship as a genuine political bond, and with Derrida's development of that view via an exploration of (...) Aristotle's alleged and provocative announcement 'O my friends, there is no friend'. Tensions between love and respect, identity and difference, a focus on the self and a focus on the other are closely examined.From Aristotle to contemporary theorists, the book explores the conditions that enable the development of self-understanding in friendship, the delicate and unstable pairing of concepts like inclination and duty and distinctions between self-love, self esteem and self-concern in relations between friends.Key Features* Recognition of the variety of the term 'friend' in the history of philosophy* The treatment of the tension between identity and difference in relations between friends* Discussion of the contribution of friendship to self-understanding. (shrink)

This paper aims at elucidating the present strength of the social and political ideas one can draw from Wittgenstein’ later work, rooting in it his conception of the subjectivity of language and of the speakers’ authority and voice; of the I and the us. The article uses the concept of forms of life – understood, following Stanley Cavell and Veena Das, not only in the social sense but also in the natural sense, as life forms. – in order to rearticulate (...) the natural and conventional and to perceive, as Cavell puts it, “the mutual implication of the natural and the social” in the constitution of us – and in a renewed, ordinary conception of democracy. (shrink)

ABSTRACT In this article, we address the aporia(s) of the Olympic discourse produced by the troubled split between sport and politics. To start our argument, we will show that sporting governing bodies continuously insist that they are still on the other side of any kind of politics. Guided by Aristotle, who presented the reciprocity of ethics and politics, we will unveil the fallacy of this discourse. In a short genealogy of the relationship between sport, ethics, and politics, we will highlight (...) the Munich Olympics 1936 and Mexico Olympics 1968, where political engagement of sport was exposed clearly. At the same time, the supposed political neutrality of sport manifested an aristocratic preference for radical right regimes. After that, we will analyse the contemporary relation between sport, ethics, and politics in the light of recent developments, including sport’s ambiguous reaction on the Ukraine war. Further argument will be that sport’s in- and external politics, supported by sport ethics and the inherited mantra of the split between sport and politics, is more than just a hypocrisy. At the start, modern sport claims autonomy of governance to keep away from state domination, yet this very autonomy also freezes sport’s ethical core, forbidding athletes, coaches and others active in sport, to express any political engagement, other than passive acceptance of the regulation by governing sport bodies, as the only politics to be respected without deliberation. In the final part an alternative understanding of the dynamics between politics, the political and sport’s ethical core, will be presented to be included in the philosophy of sport and fully developed in following articles. (shrink)

The aim of this Special Issue is to mobilize the theoretical tools and methods of Wittgenstein’s philosophy within feminist and queer studies. Focusing on Wittgenstein – in contrast to Austin, who has often been mobilized within feminist theories – seems to be helpful to underline the Wittgensteinian understanding of language, distinct from the way some poststructuralist feminisms conceive of “discourse”, ideology or the material dimensions of language.

This conceptual paper argues that change makers, here called transformation stewards, attempting to catalyze transformational change need three core skillsets specific to stewarding transformative change, and further argues that mindfulness practices can potentially enhance these capacities. One skillset is reflexive systems-based awareness and understanding. Another includes capacities for fostering what gives life in complexly wicked social-ecological systems. A third is having capacity for and willingness to steward whole system change, rather than lead it in the conventional sense, which is made (...) necessary because of the nature of organizing transformation stewards in complex, life-oriented systems. Tentative evidence from the literature supports the idea that a combination of experience and mindfulness practices of various sorts can enhance these capabilities. (shrink)

Although from diverse times and backgrounds, Confucius in the sixth century b. C. In china and immanuael kant in enlightenment both set forth doctrines for ethics and positive social interaction which revolve around the concept of respect. For confucius, Respect takes the form of "jen", What "ought" to occur when two people come together. Individuals are respected as social beings. In kant's case the principle of humanity demands respect for human beings "qua" rational. The difference reveals confucian dynamism versus kantian (...) universalism, Each keynotes of the respective cultural contexts. (shrink)

The concept of form of life is simultaneously and inseparably overvalued and neglected in Wittgenstein’s work. The author aims to understand the concept of form of life, or lifeform (as Cavell proposes to translate Lebensform), as an alternative to the concept of rules in the exploration of ordinary language. Cavell shows at once the fragility and the depth of our agreements, and he seeks out the nature of the necessities that emerge from our forms of life. Ordinary language philosophy as (...) inherited by Cavell is thus anchored in an attention to language as it is commonly used, as part and milieu of our everyday interactions and conversations. Attention to ordinary language is also attention to neglected realities and to the constant risk of failure of conversation in everyday life. Recognizing the vulnerability of language - excuses, e. g., in their everyday recognition of human vulnerability and tragedy - allows us to recognize the human lifeform as itself vulnerable. Contemporary philosophy often sees recourse to the ordinary, to forms of life (as given), as a too-easy solution to skepticism. But the threat of destruction of forms of life (social and biological) in the present world gives the concept of Lebensform renewed reality and relevance: It is to turn us toward the unending political evaluation of the confrontation between need and rule, and to compare this with Emerson’s recurrence to the collisions of power and form, that I have urged noticing the key ambiguity in Wittgenstein’s concept of a form of life. The concept projects simultaneously, as I take it, an irreducibly horizontal ethnological or conventional axis crossing an irreducibly vertical biological axis,which is in effect to picture human existence as that life form which eternally criticizes itself - as it were from below and from beyond - or incessantly declines to. (Cavell 2010: 108). (shrink)

The problem is pain. Patients and their families tell the story:He is your son. You love him. You want to help him in every way you can, but when he is in that kind of pain, you are helpless in a sense. Im his daddy. It was-what was I supposed to do for him? I felt, you know, helpless.It terrifies you. You want to run away from it. Pain is something you wish would kill you but does not. Agony results (...) from the pain that does not have the decency to knock you out.[W]e had a good family, but how much can you watch? How much suffering can you watch from your child, your 7-year-old child, and still keep your mind?I am a forty-six-year-old registered nurse who specializes in oncology care and education. I am also a patient who suffers from chronic nonmalignant pain, and this malady has been the most frightening, the most humiliating, and the most difficult ordeal of my life. (shrink)

A study of experienced teachers is used to illustrate a developmental methodology for promoting technical performance dimensions and moral and conceptual reasoning based on Sprinthall's and Thies-Sprinthall's (1983) principles of new social role-taking and guided inquiry. Called the learning-teaching framework (LTF), the theoretical and applied approach embeds new role-taking, guided inquiry, balance, support and challenge, continuity and instructional coaching in educational programming across the teacher professional development career span. The study was a 7-month quasi-experimental intervention of expert teachers participating in (...) a professional development program to support peer coaching (e.g. a form of collaborative inquiry which prompts teachers to initiate complex new roles as peer coaches in which they plan, demonstrate and practise new models of teaching). The aims of the study were to encourage new social role-taking, support new learning in effective teaching, encourage new complex performances in coaching and support conferences, and promote gains in moral and conceptual reasoning. Significant positive gains in learning, performance and moral judgement reasoning were achieved. The study highlights the benefits of using the LTF as a framework for educational programming and teacher character development programmes that are based on similar theoretical assumptions. (shrink)

The frequency of the use of deception in American psychological research was studied by reviewing articles from journals in personality and social psychology from 1921 to 1994. Deception was used rarely during the developmental years of social psychology into the 1930s, then grew gradually and irregularly until the 1950s. Between the 1950s and 1970s the use of deception increased significantly. This increase is attributed to changes in experimental methods, the popularity of realistic impact experiments, and the influence of cognitive dissonance (...) theory. Since 1980 there appears to have been a decrease in the use of deception as compared to previous decades which is related to changes in theory, methods, ethical standards, and federal regulation of research. (shrink)

Recent "gender, environment, and sustainable development" accounts raise pointed questions about the complicity of Enlightenment philosophies of science with failures of Third World development policies and the current environmental crisis. The strengths of these analyses come from distinctive ways they link androcentric, economistic, and nature-blind aspects of development thinking to "the Enlightenment dream." In doing so they share perspectives with and provide resources for other influential schools of science studies.

English summary: Through the concept of the ordinary, and what is ordinary, the present volume explores contemporary American philosophy. More specifically, the author presents Stanley Cavells role at the center of this movement to examine its innovative approach to philosophy, one that draws on what we have at hand, but also seeks to discover and invent. French description: Savons-nous vraiment ce qu'est l'ordinaire, ce qui nous est ordinaire? Penser la philosophie americaine, et le role qu'a son coeur joue Stanley Cavell, (...) signifie poser de nouveau ces questions, afin de mettre en evidence une nouvelle voix ou tradition contemporaine qui, a partir du langage ordinaire, parvient a redonner de la vie a des enjeux philosophiques devenus trop conformistes ou etroits, et a rearticuler les questions de langage (ordinaire) au moral et a l'esthetique, comme au politique. A la fois objet de rejet et de fascination, l'ordinaire est comme l'autre de la philosophie, ce qu'elle veut, dans son arrogance, depasser, mais aussi ce vers quoi elle aspire, nostalgiquement, a retourner. Penser la philosophie americaine signifie repenser l'ordinaire en dehors de ces deux tendances: recommencer la philosophie, non pas a zero, mais avec ce qu'on a sous la main, sous les yeux, et qui reste a decouvrir, ou a inventer. (shrink)

El artículo es una creación en la que convergen las experiencias, indagaciones, discusiones suscitadas en los antecedentes y el desarrollo del Proyecto “Investigar, leer y escribir en la universidad:el docente investigador mediador y aprendices investigadores autónomos”, que identifica la problemática sobre la orientación de investigación formativa en pregrado, en la relación docencia-investigación; así, formula la pregunta directriz ¿Cómo orientar el proceso de investigación formativa en la formulación de proyectos de investigación? La propuesta recoge la experiencia docente e investigativa en lectura, (...) escritura, procesos de mediación y autorregulación. Además, reconoce la necesidad de articular los proyectos de investigación estudiantiles, planteados comotrabajos de grado, al sistema de investigación universitario. (shrink)

Biblical spirituality must strike a delicate balance between historical-critical engagement with scripture and opening oneself to the Word's life-transforming potential.

INTRODUCTION In the philosophic world today, and especially within the context of the emerging American scene, pragmatism and phenomenology can each ...

The capacity to treat pain has never been greater; but, as you will read in the articles that follow, the problem of undertreated and neglected pain in the United States persists. Deep-seated perceptions and practices undergird this strong and well-documented pattern of neglect. Among the reasons frequently noted for the inadequacy of treatment for pain, however, is that the legal system actually penalizes effective interventions to relieve pain while it leaves neglect of pain unthreatened. It is the mission of the (...) American Society of Law, Medicine & Ethics to explore areas, such as this one, where developments in medicine directly encounter the law and, in turn, create ethical issues for clinicians, regulators, patients, and lawyers.This special issue of the Journal of Law, Medicine & Ethics is part of a multi-year project in which ASLME, with the wonderful support of the Mayday Fund, has worked to address legal and regulatory barriers to effective pain relief. (shrink)