Climbazole
 | |
| Clinical data | |
|---|---|
| Routes of administration | topical |
| ATC code |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.048.870 |
| Chemical and physical data | |
| Formula | C15H17ClN2O2 |
| Molar mass | 292.76 g·mol−1 |
| 3D model (JSmol) | |
| Chirality | Racemic mixture |
| |
| |
  (what is this?) (verify) | |
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema.[2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff.[2] Its chemical structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole.
Indications and formulations
[edit]It is most commonly found as an active ingredient in OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.[citation needed]
Side effects
[edit]It may cause localized irritation of the skin with symptoms including redness, rashes and itching.[citation needed]
See Also
[edit]References
[edit]- ^ Chemical Properties of Climbazole Archived 2007-11-13 at the Wayback Machine
- ^ a b Wigger-Alberti W, Kluge K, Elsner P (August 2001). "[Clinical effectiveness and tolerance of climbazole containing dandruff shampoo in patients with seborrheic scalp eczema]". Praxis. 90 (33): 1346–9. PMID 11534318.