Decline in the AIDS and death rates in the EuroSIDA study: an observational study
@article{Mocroft2003DeclineIT,
title={Decline in the AIDS and death rates in the EuroSIDA study: an observational study},
author={Amanda Mocroft and Bruno Ledergerber and Christine Katlama and Ole Kirk and Peter Reiss and A d'Arminio Monforte and Brygida Knysz and Manfred Dietrich and Andrew N Phillips and Jens D. Lundgren},
journal={The Lancet},
year={2003},
volume={362},
pages={22-29},
url={https://api.semanticscholar.org/CorpusID:26157673}
}1,321 Citations
Differential improvement in survival among patients with AIDS after the introduction of HAART
- 2007
Medicine
Substantial improvements in survival after the introduction of HAART were found for all PWA but varied by specific ADIs and the degree of immunosuppression, and was marked during the late HAART period across all HIV transmission categories, including intravenous drug use.
Trends of Mortality and Cause of Death among HIV-Infected Patients in Korea, 1990-2011
- 2013
Medicine
Despite of significant improvement of survival, there was still a high risk of early death in patients presenting in HAART era, mainly due to late human immunodeficiency virus (HIV) diagnosis and late presentation to care.
Mortality in the Highly Active Antiretroviral Therapy Era: Changing Causes of Death and Disease in the HIV Outpatient Study
- 2006
Medicine
Although overall death rates remained low through 2004, the proportion of deaths attributable to non- AIDS diseases increased and prominently included hepatic, cardiovascular, and pulmonary diseases, as well as non-AIDS malignancies.
The changing incidence of AIDS events in patients receiving highly active antiretroviral therapy.
- 2005
Medicine
Although the incidence of all AIDS-defining events decreased substantially after starting HAART, the pattern of decline was most pronounced for events with a viral etiology, suggesting that changes in these markers did not fully explain the changes in incidence seen.
Regional Differences in AIDS and Non-AIDS Related Mortality in HIV-Positive Individuals across Europe and Argentina: The EuroSIDA Study
- 2012
Medicine
There are significant differences in the rate of all-cause mortality among HIV-positive individuals across different regions of Europe and Argentina and these findings are important for understanding and reviewing HIV treatment strategies and policies across the European region.
Improved survival of persons with human immunodeficiency virus type 1 infection in the era of highly active antiretroviral therapy in Taiwan.
- 2006
Medicine
It is suggested that the survival of persons in the late stage of HIV infection in Taiwan continued to improve in the early-HAART era and in theLate HAART era.
HIV in Denmark and Greenland, 1995–2004, the effect of highly active antiretroviral therapy and characteristics of the HIV-infected population: an observational study
- 2006
Medicine
The aims of this thesis were to examine temporal trends in deaths, new infections, and individual patients characteristics among the Danish HIV-infected population, and to estimate acquisition of antiretroviral drug-resistant virus over time.
Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina Reekie,
- 2018
Medicine
There are significant differences in the rate of all-cause mortality among HIV-positive individuals across different regions of Europe and Argentina, and Individuals in Eastern Europe had an increased risk of mortality from AIDS related causes and individuals in North Europe had the highest rate of non-AIDS related mortality.
Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy
- 2007
Medicine
A significant and progressive decrease in mortality and increase in life expectancy were observed over the 12-year study period and were directly associated with the use of modern forms of HAART.
29 References
Changes in the cause of death among HIV positive subjects across Europe: results from the EuroSIDA study
- 2002
Medicine
The proportion of pre-AIDS deaths increased from 1994 to 2001; however, the incidence of pre -AIDS deaths and deaths overall declined; therefore, it is essential to continue to monitor all causes of mortality to identify changes.
Changes in use of antiretroviral therapy in regions of Europe over time
- 1998
Medicine
Use of antiretroviral therapy in Europe has changed dramatically towards combination treatment in the last few years, and regional differences in use of antifiltration therapy have decreased, and by September 1997 only minor differences remained.
Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study
- 1997
Medicine
The introduction of antiretroviral combination therapies outside the selected patient groups included in clinical trials has led to comparable reductions in disease progression and mortality in Switzerland.
Regional differences in use of antiretroviral agents and primary prophylaxis in 3122 European HIV-infected patients. EuroSIDA Study Group.
- 1997
Medicine
ARV therapy was more frequently used among patients from southern and central Europe as compared with patients from northern Europe, especially among patients with CD4 counts >200 cells/microl, and antifungal therapies are used differently in different parts of Europe.
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.
- 1998
Medicine
The recent declines in morbidity and mortality due to AIDS are attributable to the use of more intensive antiretroviral therapies.
Highly Active Antiretroviral Therapy in a Large Urban Clinic: Risk Factors for Virologic Failure and Adverse Drug Reactions
- 1999
Medicine
The hypothesis was that the virologic response to HAART would be substantially worse among unselected patients in an inner-city clinic than among patients enrolled in clinical trials, and this study analyzed data from a cohort of protease inhibitor-naive patients in whom HAART was initiated in the clinic between March 1996 and February 1998.