Prevalence and clinical relevance of local allergic rhinitis

@article{Rondn2012PrevalenceAC,
  title={Prevalence and clinical relevance of local allergic rhinitis},
  author={Carmen Rond{\'o}n and Paloma Campo and Luisa Galindo and Natalia Blanca‐Lopez and Maria Salas Cassinello and Jos{\'e} Luis Rodr{\'i}guez-Bada and M J Torres and Miguel Blanca},
  journal={Allergy},
  year={2012},
  volume={67},
  url={https://api.semanticscholar.org/CorpusID:22470654}
}
Evidence demonstrates the existence of local allergic rhinitis (LAR) in nonatopic patients, although its prevalence in the rhinitis population remains unknown. The aim, therefore, of this study was…
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169 Citations

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25 References

Atypical nasal challenges in patients with idiopathic rhinitis: more evidence for the existence of allergy in the absence of atopy?

This study compares detailed nasal challenge results obtained from patients with idiopathic rhinitis to those of atopic and normal controls.

Seasonal idiopathic rhinitis with local inflammatory response and specific IgE in absence of systemic response

N nasal mucosa inflammation, the presence of nasal specific‐IgE and the response to nasal allergen provocation test (NAPT) in patients with seasonal IR who presented symptoms only in spring are examined.

Evidence for an inflammatory pathophysiology in idiopathic rhinitis

This work has shown that persistent idiopathic rhinitis has a Th2 type inflammatory pathology mediated by IgE and mast cells, and the disease is classified as being non‐allergic on the basis of negative serum IgE radioallergosorbent assay (RAST) and skin prick tests.

‘Entopy’: localized mucosal allergic disease in the absence of systemic responses for atopy

The Th2 immune response in the nasal mucosa of subjects with allergic rhinitis is mediated by allergen‐specific IgE, and subjects with similar histological nasal mucosal features differ in being defined as non‐allergic because they have negative atopic responses.

LOCAL PRODUCTION OF SPECIFIC IgE ANTIBODIES IN ALLERGIC-RHINITIS PATIENTS WITH NEGATIVE SKIN TESTS

Differences between allergic and nonallergic rhinitis in a large sample of adolescents and adults

Differences between allergic rhinitis (AR) and nonallergic rhINitis (NAR) in a large community‐based sample of Danish adolescents and adults are described.

Immediate and dual response to nasal challenge with Dermatophagoides pteronyssinus in local allergic rhinitis

Background Local allergic rhinitis (LAR) is characterized by in situ production of specific IgE (sIgE) antibodies and a positive response to a nasal allergen provocation test (NAPT) in the absence of…

Relationships between rhinitis and asthma

Although the nasal and bronchial mucosa present similarities, there are also differences which might suggest that rhinitis and asthma are two different airway diseases.

Update on nonallergic rhinitis.

Seasonal non-allergic rhinitis (SNAR)--a new disease entity? A clinical and immunological comparison between SNAR, seasonal allergic rhinitis and persistent non-allergic rhinitis.

SNAR seems to be different from SAR and PNAR regarding immunological mechanism and symptom period, and it is concluded that the cause of SNAR is unknown.