Nuclear Receptors: The Evolution of Diversity

@article{Schwabe2004NuclearRT,
  title={Nuclear Receptors: The Evolution of Diversity},
  author={John W. R. Schwabe and Sarah A. Teichmann},
  journal={Science's STKE},
  year={2004},
  volume={2004},
  pages={pe4 - pe4},
  url={https://api.semanticscholar.org/CorpusID:20835274}
}
The recent cloning, from a snail, of an estrogen receptor that does not bind estrogen suggests that the steroid receptors are much more ancient than previous thought, and points toward a mechanism through which nuclear receptors can lose the ability to be ligand regulated.
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29 References

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