The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder
@article{Bora2011TheEO,
title={The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder},
author={Emre Bora and Alex Fornito and Murat Y{\"u}cel and Christos Pantelis},
journal={Psychological Medicine},
year={2011},
volume={42},
pages={295 - 307},
url={https://api.semanticscholar.org/CorpusID:206252132}
}Background Recent evidence from genetic and familial studies revitalized the debate concerning the validity of the distinction between schizophrenia and bipolar disorder. Comparing brain imaging findings is an important avenue to examine similarities and differences and, therefore, the validity of the distinction between these conditions. However, in contrast to bipolar disorder, most patient samples in studies of schizophrenia are predominantly male. This a limiting factor for comparing…
133 Citations
Neuroanatomical voxel-based profile of schizophrenia and bipolar disorder
- 2016
Psychology, Medicine
The present review summarises the findings of the voxel-based grey matter comparisons between SCZ and BD, with the objective to highlight the possible consistent anatomical differences between the two disorders.
Common and specific patterns of functional and structural brain alterations in schizophrenia and bipolar disorder: a multimodal voxel-based meta-analysis
- 2022
Psychology, Medicine
A meta-analysis of differences in regional homogeneity and voxel-based morphometry between patients and healthy controls for schizophrenia and bipolar disorder separately showed patients with schizophrenia showed more widespread functional and structural impairment, most prominently in the primary sensory motor areas.
Reduced Gray Matter Volume in Orbitofrontal Cortex Across Schizophrenia, Major Depressive Disorder, and Bipolar Disorder: A Comparative Imaging Study
- 2022
Psychology, Medicine
Examination of common OFC alterations in SZ, MDD, and BD provided evidence that this region dysregulation may play a critical role in the pathophysiology of these three psychiatric disorders.
Brain structure in schizophrenia vs. psychotic bipolar I disorder: A VBM study
- 2015
Psychology, Medicine
Gray matter volume in major depressive disorder: A meta-analysis of voxel-based morphometry studies
- 2013
Medicine, Psychology
Cingulate abnormalities in bipolar disorder relate to gender and outcome: a voxel-based morphometry study
- 2018
Medicine, Psychology
The findings further confirm the putative role of the ACC in the pathophysiology of BD and suggested the presence of gender-specific GM volume reductions in ACC in BD, which may also be associated to poor outcome.
Cognitive Impairment in Bipolar Disorder and Schizophrenia: A Systematic Review
- 2013
Psychology, Medicine
It is found that overall both SZ and BD patients present deficits on all neurocognitive measures compared to healthy controls, and patients with BD might exhibit a cognitive impairment that could be similar to SZ in terms of their profile.
123 References
Anatomy of bipolar disorder and schizophrenia: A meta-analysis
- 2010
Medicine, Psychology
Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis.
- 2009
Medicine, Psychology
There appear to be robust changes in brain volume in bipolar disorder compared with healthy volunteers, although most changes do not seem to be diagnostically specific.
Voxelwise Meta-Analysis of Gray Matter Abnormalities in Bipolar Disorder
- 2010
Medicine, Psychology
Neuroanatomical abnormalities in schizophrenia: A multimodal voxelwise meta-analysis and meta-regression analysis
- 2011
Psychology, Medicine
Sex differences in schizophrenia, a review of the literature.
- 2000
Psychology, Medicine
This review supports the presence of significant differences between schizophrenic males and females arising from the interplay of sex hormones, neurodevelopmental and psychosocial sex differences.
Title Are bipolar disorder and schizophrenia neuroanatomicallydistinct ? An anatomical likelihood meta-analysis
- 2010
Psychology
Neuroimaging studies of schizophrenia and bipolar disorder typically provide considerable data on the brain endophenotype of psychosis, however the extent to which bipolar disorder is considered separately from schizophrenia and other psychoses varies.
No change to grey and white matter volumes in bipolar I disorder patients
- 2007
Medicine, Psychology
The aim of this VBM study was to investigate grey and white matter volumes in a large sample of patients with bipolar I disorder and healthy control subjects and was not able to identify core regions of structural abnormalities in bipolar disorder.
Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study.
- 2005
Medicine, Psychology
Reductions in amygdala and accumbens volumes are consistent with neuropsychological data on pediatric BPD, which is consistent with data implicating the prefrontal cortex in emotion regulation, a process that is perturbed in BPD.
Prefrontal-temporal gray matter deficits in bipolar disorder patients with persecutory delusions.
- 2010
Psychology, Medicine
Regional Gray Matter Changes in Bipolar Disorder: A Voxel-Based Morphometric Study
- 2007
Psychology, Medicine
Evidence of gray matter volume abnormalities in adults with bipolar I disorder is presented, which suggests a neurobiological basis for clinical heterogeneity and posits the possibility of trait deficits.